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Fig. 2 | Genome Biology

Fig. 2

From: Genetic disease risks can be misestimated across global populations

Fig. 2

Known disease associations lead to misestimates of genetic disease risks. a Risk allele frequencies at published disease-associated loci from the NHGRI-EBI GWAS Catalog vary by population. “*” indicates a statistically significant allele frequency difference between African and non-African populations (p values < 0.05, paired Wilcoxon rank sum tests). n = number of disease-associated loci per disease category. b Proportion of disease-associated loci where the risk allele is ancestral, as opposed to derived

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