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Fig. 6 | Genome Biology

Fig. 6

From: Holo-Seq: single-cell sequencing of holo-transcriptome

Fig. 6

miRNA-mRNA dual transcriptome analyses of hepatocellular carcinoma (HCC) single cells. a Unsupervised hierarchical clustering analysis of 32 HCC single cells based on the top variant mRNAs and miRNAs (details in the “Methods” section). Three expression-based cell subpopulations (Exp-subpopulation) and six differential expressed gene groups were identified (dashed squares). Featured cancer-related genes are labeled on the right. b Featured cancer-related Gene Ontology (GO) terms in gene groups 1, 3, 4, and 5

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