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Table 2 Lineage restricted PFAM-A domains

From: Comparative genomics reveals the distinct evolutionary trajectories of the robust and complex coral lineages

  Domain Description   Domain Description
Present in ANEMONE not in coral DUF3445 Protein of unknown function (DUF3445) Present in COMPLEX not in robust corals BCL_N* BCL7, N-terminal conserver region
DUF853 Bacterial protein of unknown function (DUF853) SR-25* Nuclear RNA-splicing-associated protein
IF3_N Translation initiation factor IF-3, N-terminal domain Toxin_R_bind_N* Clostridium neurotoxin, N-terminal receptor binding
CHZ Histone chaperone domain CHZ DUF4557 Domain of unknown function (DUF4557)
DUF455 Protein of unknown function (DUF455) Nucleoplasmin* Nucleoplasmin
MotA_ExbB MotA/TolQ/ExbB proton channel family CBM_11* Carbohydrate binding domain (family 11)
COX7a Cytochrome c oxidase subunit VIIa Microtub_assoc* Microtubule associated
PNMA PNMA Drc1-Sld2* DNA replication and checkpoint protein
SLBB SLBB domain Prefoldin_3* Prefoldin subunit
5-nucleotidase 5′-nucleotidase CutA1* CutA1 divalent ion tolerance protein
MacB_PCD MacB-like periplasmic core domain DUF2414* Protein of unknown function (DUF2414)
Glyco_trans_4_2 Glycosyl transferase 4-like Dynein_IC2* Cytoplasmic dynein 1 intermediate chain 2
HtrL_YibB Bacterial protein of unknown function (HtrL_YibB) MIF4G_like* MIF4G like
Glyco_transf_17 Glycosyltransferase family 17 TAN* Telomere-length maintenance and DNA damage repair
DUF1762 Protein of unknown function (DUF1762) DUF2201 VWA-like domain (DUF2201)
FAM216B FAM216B protein family MGC-24* Multi-glycosylated core protein 24 (MGC-24)
Resistin Resistin Hint_2 Hint domain
DUF3598 Domain of unknown function (DUF3598) Mem_trans* Membrane transport protein
PDH Prephenate dehydrogenase DUF4606* Domain of unknown function (DUF4606)
YbjQ_1 Putative heavy-metal-binding    
CBM_20 Starch binding domain    
IF2_N Translation initiation factor IF-2, N-terminal region    
IlvN Acetohydroxy acid isomeroreductase, catalytic domain    
Present in CORAL not in anemone OLF Olfactomedin-like domain Present in ROBUST not in complex corals RAG1 Recombination-activation protein 1 (RAG1)
LRRNT Leucine rich repeat N-terminal domain DUF2341 Domain of unknown function (DUF2341)
Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain Toxin_60 Putative toxin 60
HTH_19 Helix-turn-helix domain HisG ATP phosphoribosyltransferase
Parvo_coat_N Parvovirus coat protein VP1 Glt_symporter* Sodium/glutamate symporter
ScpA_ScpB ScpA/B protein NTPase_I-T* Protein of unknown function DUF84
MFS_3 Transmembrane secretion effector XG_Ftase* Xyloglucan fucosyltransferase
BBE Berberine and berberine like Phospholip_A2_2* Phospholipase A2
LBR_tudor Lamin-B receptor of TUDOR domain Polysacc_lyase Polysaccharide lyase
HATPase_c_4 ATP-dependent DNA helicase recG C-terminal PRA-CH Phosphoribosyl-AMP cyclohydrolase
PSDC Phophatidylserine decarboxylase Sigma70_r4_2* Sigma-70, region 4
STAG STAG domain HTH_Tnp_Tc3_2* Transposase
GH3 GH3 auxin-responsive promoter IGPD* Imidazoleglycerol-phosphate dehydratase
Glutaminase Glutaminase EURL EURL protein
Smoothelin Smoothelin cytoskeleton protein Histidinol_dh Histidinol dehydrogenase
DUF1982 Domain of unknown function (DUF1982) Hexapep_2* Hexapeptide repeat of succinyl-transferase
MRP-L28 Mitochondrial ribosomal protein L28 DUF4094 Domain of unknown function (DUF4094)
Tocopherol_cycl Tocopherol cyclase HisG_C HisG, C-terminal domain
Sec39 Secretory pathway protein Sec39 DUF1864 Domain of unknown function (DUF1864)
DUF3496 Domain of unknown function (DUF3496) Phage_T7_tail Phage T7 tail fibre protein
DUF4613 Domain of unknown function (DUF4613) PRA-PH* Phosphoribosyl-ATP pyrophosphohydrolase
HK Hydroxyethylthiazole kinase family Lipase_GDSL_3 GDSL-like Lipase/Acylhydrolase family
Macro_2 Macro-like domain    
DUF72 Protein of unknown function DUF72    
SRP9–21 Signal recognition particle 9 kDa protein (SRP9)    
PMT_2 Dolichyl-phosphate-mannose-protein mannosyltransferase    
STAT_int STAT protein, protein interaction domain    
CNPase 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNP or CNPase)    
UPF0066 Uncharacterised protein family UPF0066    
Tnp_zf-ribbon_2 DDE_Tnp_1-like zinc-ribbon    
Eno-Rase_NADH_b NAD(P)H binding domain of trans-2-enoyl-CoA reductase    
CR6_interact Growth arrest and DNA-damage-inducible proteins-interacting protein 1    
BRCA-2_OB3 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3    
  1. *Domains present in Nematostella or Aiptasia. See Additional file 2: Table S14 for more detail
  2. Domains shown in italics represent domains involved in the histidine biosynthesis pathway