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Fig. 3 | Genome Biology

Fig. 3

From: Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

Fig. 3

Performance optimization by parameterization and ensembles. a Recall, precision, and F-score of all IS1 submissions plotted by team, then submission order. Teams were ranked by the F-score of their best submission, color coding (top bar) as in Fig. 2. The “Standard’” lines correspond to the reference point submission provided by Challenge organizers. b For each tumor, the improvement in F-score from the initial (“naive”) to the best (“optimized”) submissions of each team. Darker shades of blue indicate greater improvement. c For each tumor, team rankings based on their naive or optimized submissions. Larger dot sizes indicate better ranks by F-score. b, c An “X” indicates that the team did not make a submission for the specific tumor (or changed team name). d Recall, precision, and F-score of ensembles versus individual submissions for IS1. At the kth rank, the triangles indicate performance of the ensemble of the top k submissions, and the circles indicate performance of the kth ranked submission. The ensemble analysis focused on the best submission from each team

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