Fig. 1

Frequencies of induction of features at LPS-induced promoters. a The fraction of promoters (y axis) with increases in features (x axis) are shown for the genome-wide set of promoters (green) and for the LPS-induced promoters (orange). Increases in H3K4me3, H3K9K14ac, H3K27ac, H3K36me3, RNA, and Pol2 binding are observed frequently at LPS-induced promoters. Significance of differences was estimated using Fisher’s exact test; *p < 1e−4; **p < 1e−6; ***p < 1e−10. b Same as a, for enhancers. c, d Heatmaps indicating the overlap in induction of pairs of features. Colors represent p values (− log₁₀) of Fisher’s exact test. White, low overlap; red, high overlap. Plots are shown for promoters (c) and enhancers (d)