Fig. 6
From: A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1
Downstream gene network of HOXC-AS3 and a common set of target genes shared by HOXC-AS3 and YBX1. a Mean-centered, hierarchical clustering of gene transcripts altered (≥ 1.5-fold change) after knockdown of HOXC-AS3 and YBX1 in BGC-823 cells, with three replicates. b Gene ontology analysis for all genes with altered expression after knockdown of HOXC-AS3. c GSEA showed that genes in response to HOXC-AS3 knockdown are enriched for the gene sets significantly related to cell proliferation and metastasis. d Coexpression-network analysis of differentially expressed genes for knockdown of HOXC-AS3. The solid lines represent positive Pearson’s correlation, whereas the dotted lines represent negative Pearson’s correlation. The node size and node color represent the coexpression ability k-core of gene, the greater the node size, the greater the k-core value