Fig. 3
From: Interaction between the microbiome and TP53 in human lung cancer
Relative abundance of Acidovorax stratified by smoking status and histological subtype. a Relative abundance of Acidovorax stratified by smoking status in the NCI-MD (left) and TCGA (right) datasets. b Relative abundance of Acidovorax in never, former, and current smokers stratified by histological subtype in the NCI-MD (left) and TCGA (right) datasets. c Representative FISH images of tumor tissue sections using fluorescent probe specific to Acidovorax. d Quantification of Acidovorax probe reactivity (10 fields; at least 300 cells counted) showing percentage (%) of cells with perinuclear probe reactivity from two lung cancer cases (15,713 – SCC/current smoker; 20,172 – SCC/former smoker). *p < 0.05, **p < 0.01, ****p < 0.0001. Tests of significance are Mann–Whitney or Kruskal–Wallis and Dunn’s multiple comparisons test. NS non-significant