Fig. 3

Evolutionary conservation of metabolic and regulatory pathways. a Heatmap showing the distribution of different types of predicted transcription factors in S. mediterranea and eukaryotes from PhyloPro v2. The numbers represented are for protein predictions of transcripts in the definitive transcriptome for S. mediterranea and proteins for all other eukaryotes. b Heatmap showing the distribution of % conservation of the major classes of KEGG metabolic pathways in S. mediterranea, human, mouse, C. elegans, and closely related Platyhelminthes