Fig. 6
From: HiGlass: web-based visual exploration and analysis of genome interaction maps
The data flow and user interface of HiGlass. Starting from the bottom-left, single resolution formats used for genomics data are converted to their multi-resolution counterparts. Files in the bigWig format, which is a native multi-resolution format, are directly converted to the hitile format compatible with HiGlass. The multi-resolution files are then loaded into the HiGlass server using a command line tool. The HiGlass client (top half) communicates with the server by issuing “tile requests” for the data that are currently visible in the user’s browser. The server responds with raw data which the client renders into vertical, horizontal, and 2D tracks. Within the client, users can zoom and pan around the data or select views with which to synchronize the location, zoom level, or both. View synchronization is initiated from one view and tied to another