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Fig. 3 | Genome Biology

Fig. 3

From: Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline

Fig. 3

Rates of spontaneous DSBs increase at LAPs, also when no promoter or enhancer sequence is present. The overlap, per kilobase, with NHEK DSB regions is shown for NHEK LAPs that overlap the following ENCODE chromHMM annotations: NHEK promoters (762 LAPs), NHEK enhancers (1485 LAPs), or neither NHEK promoters or NHEK enhancers (2030 LAPs). The dashed line indicates the genome-wide average

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