Fig. 3
The relationship between codon biosynthetic cost and codon translational efficiency in E. coli. The top panel contains a bar chart that shows the relative biosynthetic cost (green bars) and relative translational efficiency (grey bars) of each synonymous codon for each amino acid. The bottom panel contains scatter plots of this cost-efficiency data for each amino acid with multiple synonymous codons. The shading of the plots indicates the slope of the fitted line between relative biosynthetic cost and relative translational efficiency. Red shading positive correlation, green shading negative correlation, grey shading no correlation. A alanine, C cysteine, D aspartic acid, E glutamic acid, F phenylalanine, G glycine, H histidine, I isoleucine, K lysine, L leucine, N asparagine, P proline, Q glutamine, R arginine, S serine, T threonine, V valine, Y tyrosine