Fig. 2
From: DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells
DNMT3A1 is enriched at distal promoter and canyon edges. a Expression levels (FPKM) determined by RNA-seq of major active isoforms of Dnmt3a: Dnmt3a1 (NM_001271753, NM_007872), Dnmt3a2 (NM_153743), and Dnmt3b: Dnmt3b1 (NM_001003961), Dnmt3b6 (NM_001003963) in WT J1 ESCs. b Relative binding enrichment between DNMTs (DNMT3A1, DNMT3A, and DNMT3B1) at different genomic features, compared to their average genomic distribution. The canyon edge corresponds to 2-kb flanking regions around canyons. DNMT3A2 and DNMT3B1 data are from [21]