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Fig. 5 | Genome Biology

Fig. 5

From: An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray

Fig. 5

Comparison of the estimated cell proportions using constrained projection/quadratic programming (CP/QP) versus the FACS measured fraction in EPIC and 450 K platforms. a Whole blood cell samples arrayed using the EPIC platform with known (FACS) fractions for the six main cell subtypes. Cell estimates were obtained using the EPIC IDOL method. b Whole blood cell samples arrayed using the Illumina 450 K platform with known (FACS) fractions for the six main cell subtypes. Cell estimates were obtained using the EPIC IDOL 450 K legacy method. c Five out of 11 observations on the longitudinal dataset run with EPIC had FACS information

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Genome Biology

ISSN: 1474-760X

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