Skip to main content
Fig. 3 | Genome Biology

Fig. 3

From: SINC-seq: correlation of transient gene expressions between nucleus and cytoplasm reflects single-cell physiology

Fig. 3

NRI-mediated attenuation of transcriptional oscillation in nucRNA. a Heatmap of the probability of RI in cytRNA and nucRNA fractions. NRI was identified in the upper right region indicated with the broken white line. b Gene ontology analysis with NRI, showing enriched functions like metabolism of RNA and RNA splicing. c, d Correlation analysis between the probability of NRI and the fold change of gene expression among cells with NRI and without NRI (Spl spliced) in nucRNA (upper panel) and cytRNA (lower panel), respectively. e Expression of seven genes that were highly regulated by NRI in nucRNA (p < 0.0003, Mann-Whitney U test), comparing with NRI vs. without NRI (Spl) in an individual fraction. f Coverage of SRSF5 and g HNRNPDL genes showing higher intron reads in the nuclear fraction. Coverages of ARGLU1, GAS5 (SNHG2), FBXO9, VAMP2, and PI4KAP1 genes are provided in Additional file 1: Figure S10

Back to article page

Genome Biology

ISSN: 1474-760X

Contact us