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Fig. 1 | Genome Biology

Fig. 1

From: Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption

Fig. 1

High-resolution direct infusion mass spectrometry (DI-MS) of blood plasma from the Fenland cohort. a High-resolution mass spectrum from a typical blood plasma sample analysed by DI-MS. chol cholesterol, lyso-PC lysophophatidylcholines, DAG diacylglycerols, CE cholesterol esters, PC phosphatidylcholines, SM sphingomyelins, TAG triacylglycerols b Principal component analysis (PCA) of samples from the Fenland cohort (green circles) and pooled quality control samples (red circles) before normalisation. c As (b) but following batch correction normalising the total intensity of QC samples across the 19 96-well-plates used to analyse the samples from Fenland. d Hopkin’s statistic of individual lipid classes reveals that only TAGs have significant substructure in the Fenland dataset. The critical value is displayed as a dashed red line. CE cholesterol esters. PE phosphatidylethanolamines, LPC lysophosphatidylcholines, SM sphingolipids, PC phosphatidylcholines, TG triacylglcerols

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Genome Biology

ISSN: 1474-760X

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