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Fig. 7 | Genome Biology

Fig. 7

From: Vex-seq: high-throughput identification of the impact of genetic variation on pre-mRNA splicing efficiency

Fig. 7

Analysis of potential mechanisms underlying splicing changes. a Violin plots showing how the directionality of a change in ESEseq score associates with splicing changes. P value is calculated using Mann-Whitney U-test. b Scatter plot demonstrating the relationship between the ESEseq score of each hexamer and the average ΔΨ of variance gaining (adding ΔΨ) or losing (subtracting ΔΨ) that hexamer. c Scatter plot showing the positive correlation between changes in 3′ splice site maximum entropy and ΔΨ. d Scatter plot showing the positive correlation between changes in 5′ splice site maximum entropy and ΔΨ. Spearman correlation coefficients and spearman correlation p values are shown in c and d

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Genome Biology

ISSN: 1474-760X

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