Fig. 2

The application of GiniClust2 and comparable methods to simulated data. a A heatmap representation of the simulated data with six distinct clusters, showing the genes permuted to define each cluster. A zoomed-in view of the rare clusters is shown in the smaller heatmap. b A comparison between the true clusters (x-axis) and clustering results from GiniClust2 and comparable methods (y-axis). Each cluster is represented by a distinct color bar. Multiple bars are shown if a true cluster is split into multiple clusters by a clustering method. c A three-dimensional visualization of the GiniClust2 clustering results using a composite tSNE plot, combining two Fano-based tSNE dimensions and one Gini-based tSNE dimension. The inset shows a zoomed-in view of the corresponding region