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Fig. 4 | Genome Biology

Fig. 4

From: OCEAN-C: mapping hubs of open chromatin interactions across the genome reveals gene regulatory networks

Fig. 4

The association between HOCIs and gene expression. a The browser view of a 40-Mb region showing the relationship between HOCI interactions and gene transcription levels. Loops indicate read pairs (GM12878 cell). b Magnification of the region highlighted in gray in a. c The model of three different types of genes. Hub gene, the promoter is a HOCI; interacting gene, the promoter interacts with a HOCI; dissociative gene, the promoter has no interaction with a HOCI. d The proportion of the three gene types within all genes or transcribed genes (“exp genes”). e Comparison of the transcription levels of the three types of genes in U266 and RPMI-8226 cells

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