Fig. 3
Development of epithelial cells sampled from intestine, liver, lung, and skin. a Principal component analysis (PCA) of epithelial cells sampled from different organs (top). Clusters are indicated by colors, and developmental stages are indicated by shapes. Heatmaps showing the top 10 DEGs of each cluster in different organs (bottom). The color key from blue to red indicates low to high gene expression, respectively. b Heatmaps showing enrichment of DEGs of all early epithelial cells (cluster1, left) and all late epithelial cells (cluster2, right). The color key from gray to brown indicates high to low P values, respectively. c Circos plots showing shared DEGs among clusters of epithelial cells. The shared genes are linked by purple lines. d Enrichment network of shared DEGs between intestine1 and liver1. Each term is indicated by a circular node. The number of input genes falling into that term is represented by the circle size and the cluster identities are represented by colors. P values based on –log10 are given in the brackets