Fig. 5

Prediction of double-strand breaks (DSBs) using different controls. a Receiver operating characteristic (ROC) curve of a random forest discriminating between promoters with DSBs and promoters without. Area under the ROC curve (AUROC) is plotted. b Precision–recall (PR) curve of the random forest used in (a). Area under the PR curve (AUPR) is plotted. c ROC curve of a random forest discriminating between gene bodies with DSBs and gene bodies without. d Precision–recall curve of the random forest used in (c). e ROC curve of a random forest discriminating between enhancers with DSBs and enhancers without. f Precision–recall curve of the random forest used in (e). g ROC curve of a random forest discriminating between 250-base bins with DSBs and 250-base bins without. h Precision–recall curve of the random forest used in (g). AUPR, area under the PR curve, AUROC area under the ROC curve, DSB double-strand break, PR precision–recall, ROC receiver operating characteristic