Fig. 1
From: Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution
Double-strand break (DSB) prediction using epigenome marks or DNA. The prediction approach has three steps. a Mapping of DSBCapture sequencing data and DSB peak calling. b Mapping of features at DSB and non-DSB sites. Features include epigenomic and chromatin data from the ENCODE project, DNA motifs from the JASPAR database, and DNA shape predictions. c Prediction of DSB sites using features. AUC area under the curve, ds double strand, DSB double-strand break, PCR polymerase chain reaction