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Fig. 2 | Genome Biology

Fig. 2

From: Precise genome-wide mapping of single nucleosomes and linkers in vivo

Fig. 2

H3Q85C cleavages map rotational positions genome-wide. Nucleosome dyad positions based on raw H3Q85C (a) and H4S47C (b) cleavage data were aligned and dinucleotide frequencies were mapped at each base pair position. The genome-wide H4S47C rotational positioning signature is irregular and much weaker than the H3Q85C signal. A strong and more regular positioning signature (c) is obtained for H4S47C data by using the “called” subset H4S47C nucleosome dyads based on stringent cutoffs [23]

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