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Fig. 1 | Genome Biology

Fig. 1

From: Genome-wide analyses reveal a role of Polycomb in promoting hypomethylation of DNA methylation valleys

Fig. 1

A global survey of DNA methylation valleys (DMVs) in various vertebrates. a University of California, Santa Cruz (UCSC) Genome Browser snapshots of various methylomes for a DMV near Foxa1 in three vertebrates: mouse [15], human [14], and zebrafish [33]. H1 human embryonic stem cell (hESC), ME mesendoderm, NPC neural progenitor cell, TBL trophoblast-like cell, MSC mesenchymal stem cell, IMR90, human fetal lung fibroblast cell line. b UCSC Genome Browser snapshot of a DMV near Sox1 at different stages of mouse development. c Gene ontology analysis of DMV genes in different vertebrates (human, mouse, and zebrafish). Examples of transcription factors shared among all three vertebrates are listed below

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Genome Biology

ISSN: 1474-760X

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