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Fig. 4 | Genome Biology

Fig. 4

From: An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression

Fig. 4

Bacteria transplantation induced a pre-obese phenotype in mice. a Study design of bacterial transplantation. b Weights of germ-free mice on either HFD or LFD that have been transplanted with either high fat bacteria (HFB) or low fat bacteria (LFB). c, d Time course and area under the curve (AUC) for IPGTT of mice in HFDHFB and HFDLFB groups. e, f Time course and AUC for IPGTT of mice in LFDHFB and LFDLFB groups. g Relative abundance of bacteria at phylum level in mice for 5 weeks with different bacterial transplantation and diets. h PCoA of unweighted Unifrac distances over time for bacteria from animals with different bacteria and diets. i PCoA of unweighted Unifrac distances at week 5 for mice with different bacteria and diets. Data are presented as mean ± standard error of the mean. n = 7–8 per group (weight and IPGTT) or 3–4 per group (16s sequencing). p < 0.05; NS non-significant

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