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Fig. 3 | Genome Biology

Fig. 3

From: An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression

Fig. 3

Diet and obesity altered HNF4α binding in colon epithelium. a Proportion of genes with different distances from HNF4α binding sites to TSS. b HNF4α binding site distribution in the genome. c Heatmap of differential HNF4α enrichment in colonic epithelium as a function of diet. d Representative genome browser shot of differentially enriched loci. e Motif analysis of differential enrichment of HNF4α. f IPA analysis of differential enrichment of Hnf4α. g KEGG analysis of different enrichment of HNF4α in HFD and LFD groups. h GSEA analysis of target gene sets of HNF4α

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