Fig. 4
From: Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers
Mature eRNAs do not show signatures of selection within the human population. Odds ratios of frequencies within the deCODE population [49] for rare (<1.5%) and common (>5%) derived alleles compared between exonic and intronic sequences for transcripts overlapping the indicated genome annotations. The numbers of informative SNPs overlapping each category are shown in the parentheses next to the axis labels. Horizontal lines indicate the 95% confidence interval of the odds ratio estimates. Odds ratios significantly greater than one indicate increased selective constraint in exonic relative to intronic sequence