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Fig. 2 | Genome Biology

Fig. 2

From: The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex

Fig. 2

circPVT1 expression in HNSCC patients and circPVT1’s role in overall survival. a–d circPVT1 expression analysis detected by RT-qPCR. a circPVT1 expression analysis in tumoral samples matched with their non-tumoral counterparts. b circPVT1 expression analysis in mut-p53 compared to wild-type samples. c circPVT1 expression analysis in mutant samples divided into tumoral samples matched with their non-tumoral counterparts. d circPVT1 expression analysis in wild-type samples divided into tumoral samples matched with their non-tumoral counterparts. meanNorm mean normalizers, MUT p53 mutation, N non-tumoral, T tumoral, WT wild type. e Kaplan-Meir analysis representing the correlation between circPVT1 expression level and overall survival (OS) in our collection of HNSCC samples. f Kaplan-Meir analysis representing the correlation between circPVT1 expression level and OS in the HNSCC cancer data set. Multivariable analysis is shown at the bottom. HR hazard ratio

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Genome Biology

ISSN: 1474-760X

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