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Fig. 4 | Genome Biology

Fig. 4

From: Functional assessment of human enhancer activities using whole-genome STARR-sequencing

Fig. 4

Gene expression levels are quantitatively associated with in chromatin accessibility and enhancer strength. a Comparison of expression levels of genes (denoted as RPKM) with different groups of enhancers nearby. Enhancers were assigned to their nearest gene (no distance cutoff). Statistical significance was calculated using Wilcox sum rank test (*p = 2.2e-16). b 3D plot comparing expression levels of nearby genes in relation to both DNase I signal and enhancer activity. Both DNase I and enhancer signals are binned into six separate groups (0–5) according to the ranks of DNase I and enhancer signals, respectively

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