Fig. 3

Functions, expression profiles, and H3K27me3 enrichment levels of gene orthologs with either plastic or constrained H3K27me3 marking. a Heatmap representation of normalized gene ontology (GO) term counts for the 1915 and 1758 gene orthologs with plastic or constrained H3K27me3 marking. Red and green indicate depletion and enrichment in comparison to all genes marked by H3K27me3, respectively. b Density plot of tissue-specific expression for gene orthologs with plastic or constrained H3K27me3 marking as estimated by Shannon entropy. The distributions are significantly different (Kolmogorov-Smirnov test p value < 0.05). Low entropy values indicate high tissue-specific expression. c Average H3K27me3 enrichment level over gene orthologs with plastic or constrained H3K27me3 marking. Color code is as in b