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Fig. 2 | Genome Biology

Fig. 2

From: Comparative epigenomics in the Brassicaceae reveals two evolutionarily conserved modes of PRC2-mediated gene regulation

Fig. 2

Sequence conservation and nucleosome occupancy of gene orthologs according to their chromatin marking status across species. a Promoter and coding sequence similarity (Ath-Aal comparisons) between gene orthologs according to their H3K27me3 or H3K4me3 marking status across species (plastic or constrained for H3K27me3 and lineage-specific or concordant for H3K4me3 marking). Only the 13,515 gene orthologs that correspond to single gene descendants in all three species are considered. Asterisks indicate significant variations of sequence similarity in relation to chromatin marking status across species (analysis of variance (ANOVA), p value < 10e-10). b Sequence enrichment (4-mers) for the promoters of the 1915 and 1758 gene orthologs with plastic or constrained H3K27me3 marking in comparison to the 9842 unmarked gene orthologs. Positive and negative Z-score values indicate higher and lower frequencies of 4-mers in comparison to unmarked gene orthologs (4-mers showing highest/lowest frequency are highlighted in red). c Nucleosome occupancy score for the 13,515 gene orthologs according to their H3K27me3 marking status

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