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Fig. 1 | Genome Biology

Fig. 1

From: The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element

Fig. 1

LINC-PINT is downregulated in cancer and it correlates negatively with malignancy. a Schematic representation of LINC-PINT (MKLN1-AS1 or LOC378805, FLJ43663 transcript variant 1). b LINC-PINT expression in colorectal (CRC) (n = 30) and normal tissue samples (n = 4). Data are obtained from GSE35602. c LINC-PINT expression in a collection of xenograft models at in vivo passages 1, 4, and 10 (P1, P4, and P10) along with originating cell lines (P0) GSE48433. d LINC-PINT expression across cancer types in non-tumoral and tumoral tissues analyzed by RNA-seq from TCGA. P values were calculated using Wilcoxon signed rank test. e LINC-PINT levels in lung adenocarcinoma tumor samples of different stages (TCGA). f Kaplan–Meier analyses of the correlations between LINC-PINT expression level and overall survival of 144 patients with lung adenocarcinoma (TCGA). Data are shown as mean ± SD

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