Fig. 4

Poly(A)-tail lengths of PABP-bound transcripts. a Comparison of poly(A)-tail lengths of PABP-bound mRNA with those of total mRNA. Otherwise, this panel is as in Fig. 3a. b Tail-length distributions of metagenes constructed from total mRNA (black) and PABP-associated mRNA (blue). c Tail-length distributions of total mRNA and PABP-associated mRNA from the indicated genes. d The differences in mean poly(A)-tail lengths observed between PABP-bound and total mRNA for each gene plotted in a (line, median; box, quartiles; whiskers, 1.5 interquartile range). e Mean poly(A)-tail lengths in the total mRNA and in PABP-bound RNA following the indicated transfections. Otherwise, this panel is as in Fig. 3d. f The negligible effects of miRNAs on mean poly(A)-tail lengths of PABP-bound RNA. Otherwise, this panel is as in Fig. 3e