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Fig. 3 | Genome Biology

Fig. 3

From: Substantial contribution of genetic variation in the expression of transcription factors to phenotypic variation revealed by eRD-GWAS

Fig. 3

Enrichment testing for eRD genes. a–c Enrichment of “regulators” among eRD genes associated with the DTA trait at various model frequency cutoffs. a, b Numbers of eRD genes associated with the DTA trait that are defined as regulators of RNA- and protein-based GRNs by Walley et al. [48]. c Numbers of eRD genes that are themselves downstream of eRD genes that are regulators from the RNA-based GRNs. d–g Enrichment of TFs among eRD genes for various traits at various model frequencies. The number of eRD genes above indicated model frequency cutoffs are shown within each plot. The red dashed lines indicate P values of 0.05

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Genome Biology

ISSN: 1474-760X

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