Fig. 2
From: Systematic identification of regulatory variants associated with cancer risk
Regulatory regions identified in the screen and validation. a Correlation of the activities for the SNP-bound regions between two screens. The p value was calculated by Wald test, p value = 2.2 × 10−16. b Validation of identified enhancers using dual luciferase reporter assay; r represents Pearson’s correlation coefficient. The p value was calculated by Wald test, p value = 2.56 × 10−14. Identified positive regulatory regions (PRE) are in red, negative regulatory regions (NRE) are in blue, and inactive fragments are in grey. c, d Enrichments of epigenetic markers in the identified PREs and NREs, respectively. The p values were calculated by Fisher’s exact test; *p value < 0.05; error bars represent the confidence interval for the odds ratio