Fig. 2
From: Alignment-free sequence comparison: benefits, applications, and tools

Alignment-free calculation of the normalized compression distance using the Lempel–Ziv complexity estimation algorithm. Lempel–Ziv complexity counts the number of different words in sequence when scanned from left to right (e.g., for s = ATGTGTG, Lempel–Ziv complexity is 4: A|T|G|TG). Description of compression algorithms in alignment-free analysis has been reviewed extensively [63]