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Fig. 5 | Genome Biology

Fig. 5

From: DESMAN: a new tool for de novo extraction of strains from metagenomes

Fig. 5

Top panel: Number of haplotypes inferred by DESMAN as a function of MAG genome length. A significant negative correlation was observed (Spearman’s test, ρ=−0.569, p-value = 0.000068). Bottom panel: SCG nucleotide divergence against genome divergence for the Tara haplotypes separated by MAG length. This gives the fractional divergence in SNVs between every pair of haplotypes (I) against the fractional divergence in 5% gene clusters across the whole genome (C). Data points are divided according to whether they derived from a MAG with genome length <1 Mbp. In a linear regression of genome divergence against nucleotide divergence, whether a MAG was <1 Mbp was a significant interaction (slope =0.11±0.02, p-value =5.95×10−9; slope interaction small = TRUE, 0.33±0.07, p-value = 3.51×10−6; overall adjusted R-squared = 0.6021, p-value =1.786×10−12). MAG metagenome-assembled genome, SCG single-copy core gene, SNV single-nucleotide variant

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