Fig. 4
From: Splatter: simulation of single-cell RNA sequencing data
Comparison of simulation models based on various datasets. For each dataset parameters were estimated and synthetic datasets generated using various simulation methods. The median absolute deviation (MAD) between each simulation and the real data was calculated for a range of metrics and the simulations ranked. A heatmap of the ranks across the metrics and datasets is presented here. We see that the Splat simulation (with and without dropout) performs consistently well, with the BASiCS simulation and the two versions of the Lun 2 simulation also performing well