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Table 2 QTLs for immune gene modules

From: An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

Module Top SNP Chr Hg19 pos.
(Mb)
Allele
(minor/major)
MAF
(avg)
P value
DILGOM07
(effect size)
P value
YFS
(effect size)
Meta
P value
VRM rs182710579 4 19768086 G/T 0.012 2.01 × 10–4 (0.05) 8.10 × 10–6 (0.02) 9.23 × 10–9
rs151234502 7 148950168 T/C 0.012 2.59 × 10–1 (0.01) 5.31 × 10–9 (0.03) 2.46 × 10–8
rs147742798 11 70947761 T/C 0.016 1.51 × 10–3 (0.04) 1.66 × 10–6 (0.02) 9.43 × 10–9
BCM rs2523489 6 31348878 T/C 0.186 1.42 × 10–1 (0.005) 5.29 × 10–8 (0.006) 6.27 × 10–8
PM rs1354034 3 56849749 T/C 0.284 7.11 × 10–14 (-0.02) 1.51 × 10–16 (-0.008) 7.35 × 10–28
rs28367734 6 3128657 A/G 0.108 5.40 × 10–4 (0.02) 2.02 × 10–5 (0.006) 5.44 × 10–8
NM rs2485364 6 159512260 C/T 0.466 1.78 × 10–3 (0.009) 6.05 × 10–7 (0.004) 3.93 × 10–9
rs13297295 9 131659724 C/T 0.085 4.26 × 10–2 (0.009) 8.39 × 10–11 (0.01) 3.93 × 10–11
rs140929198 20 38555870 A/G 0.031 2.98 × 10–2 (0.03) 8.47 × 10–9 (0.01) 1.41 × 10–9
GIMA rs2185366 8 131342722 T/C 0.421 2.0 × 10–2 (0.007) 1.52 × 10–6 (0.004) 1.05 × 10–7
  1. Modules: VRM viral response module, BCM B-cell activity module, PM platelet module, NM neutrophil module, GIMA general immune module A. MAF minor allele frequency