Fig. 2
From: An interaction map of circulating metabolites, immune gene networks, and their genetic regulation
Module and expression QTL analysis. a Manhattan plot of meta-analyzed P values from the DILGOM/YFS module QTL analysis. The lead SNP and its closest genes are noted. Each significant mQTL locus is colored by module. The horizontal dashed line represents genome-wide (meta- P value <5 × 10−8) significance. b–d Circular plots summarizing the individual gene associations (meta-P value <5 × 10−8) for the lead module QTLs in the VRM, PM, and NM. Lead SNPs and cis genes are labeled outside the ring. PM platelet module, VRM viral response module, CCLM cytotoxic cell-like module, NM neutrophil module, BCM B-cell activity module