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Fig. 1 | Genome Biology

Fig. 1

From: Data normalization considerations for digital tumor dissection

Fig. 1

Variable correlation of directly enumerated leukocyte frequencies in lung tumors and blood. a All-versus-all Pearson correlation matrix of nine distinct leukocyte subsets profiled by flow cytometry in peripheral blood mononuclear cells (PBMCs) from 20 healthy donors [6]. b Same as panel a, but for five immune subsets profiled by flow cytometry in 13 lung squamous cell carcinoma tumor biopsies [7]. a, b Leukocyte frequencies were normalized to sum to 1 prior to correlation analysis. c Same as panel b, except the frequency of each leukocyte subset was expressed as a percentage of viable singlets prior to correlation assessment. NK natural killer, TIL tumor-infiltrating leukocyte

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