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Fig. 2 | Genome Biology

Fig. 2

From: Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours

Fig. 2

Tumour GB180. a Heatmap and partial heatmap of tumour GB180 showing a balanced translocation between chromosomes 3 and 13 (t(3;13)(p24.1;q33.3)). Heatmaps were coloured by the number of interactions with the colour gradient scaled linearly from ten (blue) to 50 (red). Bins containing less than ten interactions are not represented. The small red arrows indicate amplified regions. b Read counts for amplified regions on chromosomes 7 (top) and 12 (bottom). The high peaks show a significantly higher number of reads than in the surrounding regions. EGFR, CDK4 and MDM2 oncogenes are labelled

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