Table 1 Summary of population samples and data used in this study
From: Differentiated demographic histories and local adaptations between Sherpas and Tibetans
Population | Number of samples | Number passing QC | Platform | Collected region | Altitude (m) | Source | Symbol | Panel |
|---|---|---|---|---|---|---|---|---|
Tibetan | 31 | 31 | Affy 6.0 | Qinghai (31) | ~4350 | Simonson et al. [20] | TBN.Qinghai (42) TBN.Shigatse (43) TBN.Lhasa (30) TBN.Shannan (9) TBN.Nyingchi (9) TBN.Chamdo (9) | 1, 2 |
Tibetan | 50 | 49 | Affy 6.0 | Lhasa (20), Shigatse (18), Qinghai (11) | >3000 | Peng et al. [7] | ||
Tibetan | 69 | 64 | Affy 6.0 | Lhasa (10), Chamdo (9), Nyingchi (9), Shannan (9) and Shigatse (25) | >3000 | Xu et al. [9] and newly generated in this study | ||
Sherpa | 61 | 55 | Affy 6.0 | Zhangmu Town, Shigatse (55) | ~3400 | This study | SHP.Zhangmu (55) | 1, 2 |
Sherpa | 2 | 2 | NGS | Solo-Khumbu region, Nepal (2) | ~3800 | Jeong et al. [16] | SHP.Khumbu (2) (SHPseq2 in NGS panel) | 1, NGS panel |
Sherpa | 69 | 49 | Illumina HO-Q | Solo-Khumbu region, Nepal (49) | ~3800 | Jeong et al. [16] | SHP.Khumbu (49) | 2 |
Sherpa | 5 | 5 | NGS | Zhangmu Town, Tibet. (5) | ~3400 | Lu et al. [12] | SHPseq (5) | NGS panel |
Tibetan | 33 | 33 | NGS | Lhasa (3), Chamdo (6), Nagqu (3), Nyingchi (2), Shannan (7), and Shigatse (12) | >3000 | Lu et al. [12] | TBNseq (33) | NGS panel |
HAN Chinese | 39 | 39 | NGS | Diverse region in China (39) | <2500 | Lu et al. [12] | HANseq (39) | NGS panel |
Indian | 7 | 7 | NGS | Diverse region in South Asia | <2500 | Chambers et al. [24] | IND | NGS panel |
203 worldwide populations | 2345 | 2345 | Affy HumanOri | Worldwide regions (2345) | - | Patterson et al. [22] | Followed the original paper | 1, 2 |
Tibetan | 118 | 118 | SNaPshot | Six prefectures in Tibet | >3000 | This study | - | Target-genotyping panel |
Sherpa | 78 | 78 | SNaPshot | Zhangmu Town, Tibet | ~3400 | This study | - | Target-genotyping panel |