Fig. 5

Testing of bursting kinetics by scRNA-seq and testing mean difference by bulk-tissue sequencing. a Genes that are significant from testing of shared burst frequency and allelic imbalance. *Also includes the two genes that are significant from testing of shared burst size. Change in burst frequency and burst size in the same direction leads to higher detection power of allelic imbalance; change in different directions leads to allelic imbalance testing being underpowered. b Gene Dhrs7, whose two alleles have bursting kinetics in different directions, and gene Gprc5a, whose two alleles have bursting kinetics in the same direction. Dhrs7 is significant from testing of differential allelic bursting kinetics; Gprc5a is significant from the testing of mean difference between the two alleles