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Fig. 3 | Genome Biology

Fig. 3

From: SCALE: modeling allele-specific gene expression by single-cell RNA sequencing

Fig. 3

Allele-specific transcriptional kinetics of 7486 genes from 122 mouse blastocyst cells. a Burst frequency of the two alleles has a correlation of 0.852; 425 genes show significant allelic differences in burst frequency after FDR control. b Burst size of the two alleles has a correlation of 0.746; two genes show significant allelic difference in burst size. X-chromosome genes as positive controls show significantly higher burst frequencies of the maternal alleles than those of the paternal alleles. The p values for allelic burst size difference (bottom right) are uniformly distributed as expected under the null, whereas those for allelic burst frequency difference (bottom left) have a spike below significance level after FDR control

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