Table 1 Summary of targeted bisulfite-sequencing methylome capture panel design
| Â | Total CpGs | Total regions | Total size (bp) |
|---|---|---|---|
Regulatory regions in immune cells (DNaseI hypersensitive/active chromatin) | 1,837,099 | 315,043 | 48,810,975 |
Hypomethylated footprints from immune cells (MethylSeekR) | 3,539,071 | 477,795 | 86,414,084 |
Illumina 450Â K methylation assay included regions | 1,934,175 | 328,405 | 40,853,151 |
Autoimmune SNPs from GWAS catalog | 14,572 | 7273 | 678,026 |
Unique (non-overlapping content) in custom MCC-Seq capture panel | 4,609,564 | 822,884 | 119,089,296 |