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Fig. 8 | Genome Biology

Fig. 8

From: ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data

Fig. 8

Genotypes curated for the triple-negative breast cancer data. Binary cell genotype matrices for sample SA494 over 28 genomic loci (left) and sample SA501 over 38 genomic loci (right). These are manually curated from a single cell genotype sequencing experiment [24]. Briefly, MrBayes was used to infer a consensus phylogenetic tree over the single nuclei. Then they were grouped into clades according to high probability branching splits. Finally, each clade was assigned a consensus genotype by taking the mode genotype of the clade at each genomic locus. Colour red indicates a mutated locus, while colour blue indicates a non-mutated locus

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