Fig. 2

The ROC curve comparison between BaalChIP and other allele-specific SNP finding methods: binomial test and iASeq, using a simulated data set. The BaalChIP result is shown by solid red line. Binomial test and iASeq are shown in dashed blue and black lines. The number of TFs able to bind at a given SNP and the number of reads per TF increases from TF = 3, Reads per TF = 1 (a, b, c) to TF = 5, Reads per TF = 8 (d, e, f) to TF = 15, Reads per TF = 15 (g, h, i). RAF is decreasing from 0.5 (a, d, g) to 0.3 (b, e, g) to 0.1 (c, f, i)