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Fig. 3 | Genome Biology

Fig. 3

From: Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types

Fig. 3

Gene network and pathway analysis of neutrophil-specific HVGs not mediated by cis genetic effects. Co-expression network of neutrophil-specific HVGs that did not correlate with genetic variants in cis, as reported in the BLUEPRINT Human Variation Panel. We identified three gene modules, shown in green, yellow, and red. These modules were highly enriched for important biological functions in immune cells (Additional file 5). Nodes represent genes and edges represent correlations in these genes’ expression values. Node sizes are determined by expression variability of the corresponding gene, with bigger nodes indicating higher EV values. Nodes colored in gray belong to several smaller gene clusters connecting the three main clusters of the network

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