Fig. 1

Genome overview of Aspergillus and comparative species. a Core genes, based on MCL clustering of protein sequences, and cluster membership in section Nigri and the Aspergillaceae. Pink area of pie charts indicates proteins assignable to one or more Pfam domain; white or gray areas indicate proteins with no Pfam domain. The majority of proteins conserved in Section Nigri, Aspergillaceae, or the full set of comparative fungi could be assigned to a Pfam. Contrastingly, most clade-specific proteins (occurring only in Section Nigri or Aspergillaceae) were not assignable to any Pfam. b Maximum likelihood phylogeny inferred from 149 conserved protein sequences. Organisms newly sequenced for this study are indicated in bold. All bootstrap values are 100 except where indicated. Section Nidulantes is inferred to be a sister group to section Nigri, in contrast to previous studies. Letters in green behind the strain numbers indicate the reproductive state: A asexual, S-HO sexual homothallic, S-HE sexual heterothallic. c Protein conservation, inferred from MCL clustering of proteins, indicates that the majority of proteins in Aspergillaceae have homologs in other fungi, bars showing number of proteins being aligned to individual species to the left-hand side in (b). Some 21% of proteins are specific to the Aspergillaceae, while 14% of proteins in section Nigri are specific to that clade. Organism-specific proteins make up 9% for the Aspergillaceae as a whole and 8% for section Nigri