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Table 1 Distribution of methylated Cs in transcripts of total and nuclear poly(A) RNA of ESCs and brain

From: Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain

  Fisher exact test No. of m5Cs tested
p value* Odds ratio 95% confidence interval
Total poly(A) RNA
 ESC
  5′ UTR 1.84E-37 1.74 1.60–1.88 714
  CDS 2.22E-08 0.86 0.81–0.90 2828
  3′ UTR 0.033 0.94 0.89–0.99 1775
  AUG (+/– 25 nt) 2.87E-29 2.38 2.07–2.72 225
 Brain
  5′ UTR 1.02E-81 3.51 3.13–3.94 389
  CDS 3.11E-106 0.31 0.28–0.35 399
  3′ UTR 6.02E-19 1.55 1.41–1.71 863
  AUG (+/– 25 nt) 6.93E-27 3.84 3.09–4.71 98
Nuclear poly(A) RNA
 ESC
  5′ UTR 2.49E-09 1.36 1.23–1.50 459
  CDS 3.53E-17 0.78 0.73–0.82 2337
  3′ UTR 1.31E-07 1.18 1.10–1.25 1688
  AUG (+/– 25 nt) 1.75E-30 2.57 2.19–2.96 203
 Brain
  5′ UTR 0.001 1.37 1.13–1.65 123
  CDS 1.74E-244 0.11 0.09–0.13 157
  3′ UTR 1.12E-208 6.23 5.51–7.21 1028
  AUG (+/– 25 nt) 1.98E-19 3.90 3.00–4.99 67
  1. *Significance threshold p < 0.05